Tirzepatide
Tirzepatide is a dual GIP/GLP-1 peptide studied for powerful weight loss and metabolic control.
- Significant weight & fat loss
- Powerful appetite suppression
- Improved blood-sugar control
- Better insulin sensitivity
- Reduced cravings & food noise
Tirzepatide is a dual GIP/GLP-1 peptide studied for powerful weight loss and metabolic control.
- Significant weight & fat loss
- Powerful appetite suppression
- Improved blood-sugar control
- Better insulin sensitivity
- Reduced cravings & food noise
Money Back Guarantee
If a batch tests below 99% purity, full refund on your order + testing fees.
Money Back Guarantee
If a batch tests below 99% purity, full refund on your order + testing fees.
3D Structure
Drag to rotate · scroll to zoom · right-click to translate
- CCarbon
- HHydrogen
- NNitrogen
- OOxygen
- SSulfur
Known Synonyms
Identifiers
Molecular Formula
C225H348N48O68
InChIKey
AAPYRSPHYSKGIS-MCNPHUAVSA-N
InChI
Computed Properties
3D Structure
Drag to rotate · scroll to zoom · right-click to translate
- CCarbon
- HHydrogen
- NNitrogen
- OOxygen
- SSulfur
Known Synonyms
Identifiers
Computed Properties
Tirzepatide — Research Reference
A dual GIP/GLP-1 receptor agonist studied for potent glucose control and body-weight reduction in metabolic research models.
What is Tirzepatide?
Tirzepatide is a 39-amino-acid dual agonist that activates both the GIP and GLP-1 incretin receptors — and it is among the most-published metabolic reference compounds of the past decade precisely because that dual action produces outsized effects in research models. Studies report enhanced glucose-dependent insulin secretion, improved insulin sensitivity, suppressed appetite and substantial body-weight and fat-mass reduction in animal models, generally exceeding single-receptor GLP-1 reference compounds. A C20 fatty-diacid side chain binds serum albumin to extend its stability for week-long exposure assays. Noxa Labs supplies tirzepatide as a third-party tested analytical reference material for in vitro laboratory research only. Note: this compound is supplied strictly as an analytical reference material for in vitro research by qualified professionals. It is not a pharmaceutical product, supplement, or substance for human or animal use.
Mechanism in research literature
GIP and GLP-1 are the two principal incretin hormones, and their receptors are densely expressed on pancreatic β-cells. By engaging both with a deliberately balanced potency profile, tirzepatide amplifies β-cell cAMP signalling and glucose-stimulated insulin secretion (in INS-1 and primary-islet assays) more strongly than single-receptor agonists, while GLP-1R engagement in hypothalamic circuits drives the appetite-suppression and weight readouts seen in rodent studies. Cell-culture work since 2018 has profiled its PKA/Epac2 signalling, β-arrestin recruitment and receptor-internalisation kinetics. The engineered balance between the two receptors is what mechanistically separates tirzepatide from single-receptor GLP-1 references like semaglutide.
Documented research applications
Tirzepatide is studied in pancreatic β-cell function assays, glucose-stimulated insulin secretion in INS-1 and primary-islet cultures, adipocyte differentiation and lipolysis assays in 3T3-L1 systems, hepatic lipid-metabolism research, and comparative incretin pharmacology — with insulin output, lipolysis and weight/fat endpoints recurring throughout. Researchers comparing dual versus single incretin engagement frequently study it alongside semaglutide (single GLP-1) and retatrutide (triple GIP/GLP-1/glucagon); all three are available from Noxa Labs as analytical reference materials.
Reconstitution
Reconstitute lyophilised tirzepatide with bacteriostatic water at a concentration appropriate to your assay. A common starting concentration is 5 mg/mL for a 10 mg vial reconstituted with 2 mL BAC water. Direct the diluent against the side wall of the vial; do not inject directly onto the lyophilate. Swirl gently to dissolve.
Storage & stability
Store lyophilised tirzepatide refrigerated at 2–8 °C for long-term stability. Reconstituted tirzepatide should be stored at 2–8 °C and used within 4 weeks. Do not freeze reconstituted solution unless specifically validated for your assay.
Availability in the Philippines
Tirzepatide ships from Noxa Labs Metro Manila inventory with cold-chain packaging. Nationwide delivery to Luzon, Visayas, and Mindanao destinations in 2–3 business days.
Frequently asked questions
All Noxa Labs products are supplied strictly as analytical reference materials for qualified in vitro research. They are not pharmaceutical products, food supplements, or substances for human or animal consumption.
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