KPV
KPV is an anti-inflammatory peptide studied for gut healing and calmer, clearer skin.
- Potent anti-inflammatory action
- Gut healing & IBD support
- Calmer, clearer skin
- Faster wound healing
- Balanced immune response
KPV is an anti-inflammatory peptide studied for gut healing and calmer, clearer skin.
- Potent anti-inflammatory action
- Gut healing & IBD support
- Calmer, clearer skin
- Faster wound healing
- Balanced immune response
Money Back Guarantee
If a batch tests below 99% purity, full refund on your order + testing fees.
Money Back Guarantee
If a batch tests below 99% purity, full refund on your order + testing fees.
3D Structure
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- CCarbon
- HHydrogen
- NNitrogen
- OOxygen
- SSulfur
Known Synonyms
Identifiers
Molecular Formula
C16H30N4O4
InChIKey
YSPZCHGIWAQVKQ-AVGNSLFASA-N
InChI
Sequence
KPV
Computed Properties
3D Structure
Drag to rotate · scroll to zoom · right-click to translate
- CCarbon
- HHydrogen
- NNitrogen
- OOxygen
- SSulfur
Known Synonyms
Identifiers
Computed Properties
KPV — Research Reference
A tiny α-MSH-derived tripeptide studied for strong anti-inflammatory and gut-protective effects in research models.
What is KPV?
KPV is the C-terminal tripeptide of α-MSH (Lysine-Proline-Valine) and, despite its small size, one of the most-studied anti-inflammatory peptides in immunology research. Studies consistently document it reducing inflammation — particularly in gut/colitis and inflammatory-bowel-disease models — and dampening allergic and inflammatory-cytokine responses, with the added research advantage of retaining activity after oral exposure in some models. Noxa Labs supplies KPV as a third-party tested analytical reference material for in vitro research only. Note: this compound is supplied strictly as an analytical reference material for in vitro research by qualified professionals. It is not a pharmaceutical product, supplement, or substance for human or animal use.
Mechanism in research literature
Research describes KPV acting through both melanocortin-receptor-dependent and -independent routes. With reduced MC1R binding versus full-length α-MSH, its anti-inflammatory effect is largely traced to direct intracellular activity — notably suppression of the NF-κB pathway and reduced pro-inflammatory cytokine production in cell-culture models, the mechanism behind its gut-protective readouts. Its unusual retention of activity after oral administration in some models makes it a distinctive research probe.
Documented research applications
Documented research contexts include colitis rodent models, inflammatory-bowel-disease cell-culture research, allergic-inflammation models, mast-cell-activity research, and inflammatory-cytokine profiling — with reduced inflammation and gut protection as recurring endpoints.
Reconstitution
Reconstitute lyophilised KPV with bacteriostatic water at the concentration appropriate to your assay.
Storage & stability
Lyophilised: 2–8 °C. Reconstituted: 2–8 °C, used within 4 weeks.
Frequently asked questions
All Noxa Labs products are supplied strictly as analytical reference materials for qualified in vitro research. They are not pharmaceutical products, food supplements, or substances for human or animal consumption.
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