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4.9/5 from Philippine Researchers

GHK-Cu

₱1,999₱1,899

GHK-Cu is a copper peptide studied for skin renewal, collagen production, and anti-aging.

  • Skin regeneration & anti-aging
  • Boosted collagen & elastin
  • Faster wound healing
  • Thicker, healthier hair growth
  • Antioxidant & anti-inflammatory action
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GHK-Cu

PubChem CID: 133697840

View on PubChem
GHK-Cu

3D Structure

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  • CCarbon
  • HHydrogen
  • NNitrogen
  • OOxygen
  • SSulfur

Known Synonyms

GHK-Cu300801-03-0D92812

Identifiers

Molecular Formula

C28H48CuN12O8

InChIKey

RIPDSRHLQNAZOH-XTQNZXNBSA-N

InChI

InChI=1S/2C14H24N6O4.Cu/c2*15-4-2-1-...

Computed Properties

Molecular Weight744.3
Hydrogen Bond Donor Count12
Hydrogen Bond Acceptor Count14
Rotatable Bond Count22
Exact Mass743.301404
View all properties

GHK-Cu — Research Reference

A copper-binding tripeptide studied for skin regeneration, collagen synthesis, wound healing, and anti-inflammatory effects.

What is GHK-Cu?

GHK-Cu is the copper(II) complex of the tripeptide Glycyl-L-Histidyl-L-Lysine and one of the most-studied small peptides in research, with over 500 published papers. The literature consistently documents it stimulating skin regeneration and collagen synthesis, accelerating wound healing, remodelling the extracellular matrix, dampening inflammation, and supporting hair-follicle biology — effects strong enough that gene-expression studies describe GHK-Cu shifting the activity of hundreds of human genes toward a younger, repair-ready profile. The copper-bound form is the biologically active complex behind these effects; copper binding both stabilises the peptide and is integral to its activity in cell-culture and rodent studies. Noxa Labs supplies GHK-Cu as a third-party tested research reference material. Note: this compound is supplied strictly as an analytical reference material for in vitro research by qualified professionals. It is not a pharmaceutical product, supplement, or substance for human or animal use.

Mechanism in research literature

Research links GHK-Cu's regenerative effects to several converging pathways. In dermal fibroblast cultures it upregulates collagen and glycosaminoglycan synthesis, rebuilding ECM scaffolding; it modulates metalloproteinase expression (notably MMP-2) to balance tissue turnover; it suppresses pro-inflammatory cytokine production; and cDNA-microarray work shows it resetting expression of hundreds of genes tied to repair, antioxidant defence and the DNA-damage response. Its copper-transport activity additionally supports antioxidant pathways. The Pickart & Margolina review (Int J Mol Sci, 2018) synthesises this mechanistic literature; relevant citations are linked in the Studies tab.

Documented research applications

GHK-Cu is studied across dermal regeneration and wound-healing models, hair-follicle biology, dermal fibroblast and in-vitro skin-equivalent systems, and inflammatory-pathway research — with collagen induction, faster wound closure and anti-inflammatory readouts as recurring endpoints. Cosmetic-formulation research has examined it extensively in topical contexts. We supply GHK-Cu strictly as a research reference material — not a finished cosmetic or topical product. It also appears in research-use blends with BPC-157 and TB-500 (see our Glow Blend) for laboratories studying combined dermal-repair effects.

Reconstitution

GHK-Cu has a distinctive deep blue colour due to the copper(II) complex — this is normal and expected. Reconstitute with bacteriostatic water for laboratory work. A common starting concentration is 50 mg/mL for a 50 mg vial reconstituted with 1 mL BAC water, or scale as appropriate to your assay. Protect the reconstituted solution from light during handling.

Storage & stability

Store lyophilised GHK-Cu refrigerated at 2–8 °C, protected from light. The reconstituted solution should be kept at 2–8 °C and used within 30 days. The blue copper colour should remain consistent; significant colour change may indicate degradation.

Availability in the Philippines

GHK-Cu ships from Noxa Labs Metro Manila inventory in light-protective vials with cold-chain packaging. Nationwide delivery in 2–3 business days.

Frequently asked questions

All Noxa Labs products are supplied strictly as analytical reference materials for qualified in vitro research. They are not pharmaceutical products, food supplements, or substances for human or animal consumption.

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Analytical-grade peptide reference materials for in vitro research. Third-party tested. COA-verified. PH delivery only.

Research Use Only

All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.

Noxa Labs Philippines is a research-chemical supplier operating under Republic Act 9711 (Food and Drug Administration Act of 2009). We do not manufacture, compound, dispense, or distribute pharmaceuticals, supplements, or health products subject to FDA Philippines registration. Products are supplied solely as analytical reference materials for in vitro research by qualified professionals.

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