Semax
Semax is a nootropic peptide studied for sharper focus, memory, and brain protection.
- Sharper focus & memory
- Enhanced learning & cognition
- Neuroprotection & brain health
- Reduced stress & anxiety
- Improved mood & mental clarity
Semax is a nootropic peptide studied for sharper focus, memory, and brain protection.
- Sharper focus & memory
- Enhanced learning & cognition
- Neuroprotection & brain health
- Reduced stress & anxiety
- Improved mood & mental clarity
Money Back Guarantee
If a batch tests below 99% purity, full refund on your order + testing fees.
Money Back Guarantee
If a batch tests below 99% purity, full refund on your order + testing fees.
3D Structure
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- CCarbon
- HHydrogen
- NNitrogen
- OOxygen
- SSulfur
Known Synonyms
Identifiers
Molecular Formula
C37H51N9O10S
InChIKey
AFEHBIGDWIGTEH-AQRCPPRCSA-N
InChI
Sequence
MEHFPGP
Computed Properties
3D Structure
Drag to rotate · scroll to zoom · right-click to translate
- CCarbon
- HHydrogen
- NNitrogen
- OOxygen
- SSulfur
Known Synonyms
Identifiers
Computed Properties
Semax — Research Reference
A heptapeptide nootropic studied for raising BDNF, neuroprotection, and improved cognition in research models.
What is Semax?
Semax is a synthetic heptapeptide based on an ACTH (4–10) fragment and one of the most-studied small nootropic peptides in the neuroscience literature. Research consistently documents it raising brain-derived neurotrophic factor (BDNF), protecting neurons in ischaemic (stroke) models, and improving learning and memory performance in rodent cognitive paradigms — the effects for which it is most cited. Its C-terminal Pro-Gly-Pro extension improves stability. Noxa Labs supplies Semax as a third-party tested analytical reference material for in vitro research only. Note: this compound is supplied strictly as an analytical reference material for in vitro research by qualified professionals. It is not a pharmaceutical product, supplement, or substance for human or animal use.
Mechanism in research literature
The most-cited mechanism is upregulation of BDNF and its receptor TrkB in hippocampal cultures — the neurotrophic signalling that supports neuron survival, plasticity and the cognitive readouts seen in behavioural studies. Additional research describes modulation of dopaminergic and serotonergic pathways, melanocortin-receptor activation consistent with its ACTH origin, and immune-cytokine modulation that underlies its neuroprotective effects in stroke models. Rather than binding a single canonical receptor, Semax is described acting across several neurochemical systems at once.
Documented research applications
Documented research contexts include cerebral-ischaemia rodent models, BDNF-expression studies in hippocampal culture, cognitive-performance behavioural paradigms in animal research, and neuroinflammation models — with neuroprotection and improved learning/memory as recurring endpoints.
Reconstitution
Semax is typically supplied as a nasal-delivery research solution or lyophilised powder. Reconstitute lyophilised material with bacteriostatic water at the concentration appropriate to your assay.
Storage & stability
Lyophilised: 2–8 °C. Reconstituted: 2–8 °C, used within 3–4 weeks.
Frequently asked questions
All Noxa Labs products are supplied strictly as analytical reference materials for qualified in vitro research. They are not pharmaceutical products, food supplements, or substances for human or animal consumption.
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