PT-141
PT-141 is a peptide studied for enhanced libido and sexual performance in both men and women.
- Enhanced libido & arousal
- Improved sexual performance
- Works for both men & women
- Centrally-acting (brain pathway)
- Boosted desire & confidence
PT-141 is a peptide studied for enhanced libido and sexual performance in both men and women.
- Enhanced libido & arousal
- Improved sexual performance
- Works for both men & women
- Centrally-acting (brain pathway)
- Boosted desire & confidence
Money Back Guarantee
If a batch tests below 99% purity, full refund on your order + testing fees.
Money Back Guarantee
If a batch tests below 99% purity, full refund on your order + testing fees.
3D Structure
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- CCarbon
- HHydrogen
- NNitrogen
- OOxygen
- SSulfur
Known Synonyms
Identifiers
Molecular Formula
C50H68N14O10
InChIKey
FFHBJDQSGDNCIV-MFVUMRCOSA-N
InChI
Sequence
XDHFRWK
Computed Properties
3D Structure
Drag to rotate · scroll to zoom · right-click to translate
- CCarbon
- HHydrogen
- NNitrogen
- OOxygen
- SSulfur
Known Synonyms
Identifiers
Computed Properties
PT-141 — Research Reference
A melanocortin MC4R agonist (bremelanotide) studied for centrally-driven sexual-arousal responses in research models.
What is PT-141?
PT-141 — also known as bremelanotide — is a synthetic cyclic heptapeptide from the α-MSH lineage, studied chiefly for its effects on sexual-arousal pathways via the melanocortin system. Unlike vascular approaches, research describes PT-141 acting centrally through MC4R signalling in the brain, the mechanism for which it is most cited. It engages melanocortin receptors with a preference for MC3R/MC4R and is a standard reference compound in melanocortin-receptor pharmacology and structure-activity work. Noxa Labs supplies PT-141 as a third-party tested analytical reference material for in vitro research only. Note: this compound is supplied strictly as an analytical reference material for in vitro research by qualified professionals. It is not a pharmaceutical product, supplement, or substance for human or animal use.
Mechanism in research literature
PT-141 binds melanocortin receptors with a selectivity profile distinct from natural α-MSH: cell-culture work documents preferential MC4R agonism with markedly reduced MC1R binding, a shift driven by its cyclised heptapeptide backbone. MC4R activation in central melanocortin circuits is the pathway research links to its arousal-related effects, and that reduced MC1R activity is what differentiates it sharply from the pan-melanocortin agonist Melanotan II in melanocyte assays. This receptor-selectivity profile is the defining, most-studied feature of the molecule.
Documented research applications
Documented research contexts include MC3R/MC4R signalling assays, melanocortin-receptor binding studies, central melanocortin-circuit research, comparative melanocortin pharmacology against Melanotan II and α-MSH, and SAR research across the cyclic melanocortin family.
Reconstitution
Reconstitute lyophilised PT-141 with bacteriostatic water. Common concentrations are 10 mg/mL for a 10 mg vial in 1 mL BAC water. Direct diluent against the vial wall and swirl gently.
Storage & stability
Store lyophilised at 2–8 °C. Reconstituted solution at 2–8 °C, used within 4 weeks.
Frequently asked questions
All Noxa Labs products are supplied strictly as analytical reference materials for qualified in vitro research. They are not pharmaceutical products, food supplements, or substances for human or animal consumption.
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