NAD+
Nicotinamide Adenine Dinucleotide | Metabolic & Mitochondrial Research
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NAD-202602-J1
Purity
Tested
Third-party TestedCOA VerifiedCold StorageSame-day DeliveryNAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme present in all living cells, functioning as a critical electron carrier in metabolic redox reactions. With a molecular weight of 663.4 g/mol, molecular formula C21H27N7O14P2, and CAS number 53-84-9, NAD+ serves as a substrate for sirtuin deacetylases (SIRT1-7) and poly(ADP-ribose) polymerases (PARPs), placing it at the center of published research into cellular energy metabolism, DNA repair signaling, and mitochondrial function. Peer-reviewed studies have examined the role of NAD+ in age-related metabolic pathway changes, circadian rhythm regulation, and neuronal calcium signaling. This compound is supplied as a high-purity research reagent for enzymatic assays and in vitro investigations. It is not intended for human or veterinary use, and no claims regarding therapeutic or anti-aging efficacy are made or implied.
NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme present in all living cells, functioning as a critical electron carrier in metabolic redox reactions. With a molecular weight of 663.4 g/mol, molecular formula C21H27N7O14P2, and CAS number 53-84-9, NAD+ serves as a substrate for sirtuin deacetylases (SIRT1-7) and poly(ADP-ribose) polymerases (PARPs), placing it at the center of published research into cellular energy metabolism, DNA repair signaling, and mitochondrial function. Peer-reviewed studies have examined the role of NAD+ in age-related metabolic pathway changes, circadian rhythm regulation, and neuronal calcium signaling. This compound is supplied as a high-purity research reagent for enzymatic assays and in vitro investigations. It is not intended for human or veterinary use, and no claims regarding therapeutic or anti-aging efficacy are made or implied.
For Research Purposes Only
By purchasing this product, you acknowledge that you are a qualified researcher. Not for human or animal consumption.
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2D Structure
Known Synonyms
Identifiers
Molecular Formula
C21H28N7O14P2+
InChIKey
BAWFJGJZGIEFAR-NNYOXOHSSA-O
InChI
Computed Properties
2D Structure
Known Synonyms
Identifiers
Computed Properties
NAD+ — Research Reference
Nicotinamide adenine dinucleotide — a foundational cellular cofactor in energy metabolism, sirtuin signalling, and longevity research.
What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is one of the most fundamental cofactors in cellular biochemistry — central to redox reactions in glycolysis, the TCA cycle, and oxidative phosphorylation, and an obligatory substrate for sirtuin deacylases, PARPs, and CD38. Noxa Labs supplies NAD+ as a high-purity research reference material for in vitro laboratory work in metabolic and longevity research contexts. Despite being categorised as a "supplement" in some commercial markets, NAD+ as supplied here is strictly a research-grade reference material.
Mechanism in research literature
NAD+ functions in two largely independent biochemical roles. As a redox cofactor it shuttles electrons in metabolic pathways through reduction to NADH. As a sirtuin substrate it is consumed during deacylation reactions on histone and non-histone substrates, regulating chromatin state, mitochondrial biogenesis, and stress responses. The cellular NAD+/NADH ratio is a tightly controlled metabolic state variable, and supplementation studies in cell-culture and animal research investigate the consequences of altering this ratio.
Documented research applications
Documented research contexts include sirtuin enzymatic assays, cellular bioenergetics research, ageing and senescence models, and metabolic pathway studies. NAD+ is also commonly used as a reference in enzymology research as a substrate or product of redox reactions.
Reconstitution
Reconstitute lyophilised NAD+ with bacteriostatic water at the working concentration appropriate to your assay.
Storage & stability
Lyophilised: 2–8 °C protected from light. Reconstituted NAD+ degrades faster than peptides — use within 2 weeks at 2–8 °C, or freeze in aliquots for longer-term storage.
Frequently asked questions
All Noxa Labs products are supplied strictly as analytical reference materials for qualified in vitro research. They are not pharmaceutical products, food supplements, or substances for human or animal consumption.
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