Melanotan II
Melanotan II is studied for a deeper, longer-lasting tan with less sun exposure — plus libido support.
- Deeper, longer-lasting tan
- Less UV exposure needed
- Enhanced libido
- Appetite reduction
- More even skin pigmentation
Melanotan II is studied for a deeper, longer-lasting tan with less sun exposure — plus libido support.
- Deeper, longer-lasting tan
- Less UV exposure needed
- Enhanced libido
- Appetite reduction
- More even skin pigmentation
Money Back Guarantee
If a batch tests below 99% purity, full refund on your order + testing fees.
Money Back Guarantee
If a batch tests below 99% purity, full refund on your order + testing fees.
3D Structure
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- CCarbon
- HHydrogen
- NNitrogen
- OOxygen
- SSulfur
Known Synonyms
Identifiers
Molecular Formula
C50H69N15O9
InChIKey
JDKLPDJLXHXHNV-MFVUMRCOSA-N
InChI
Sequence
XDHFRWK
Computed Properties
3D Structure
Drag to rotate · scroll to zoom · right-click to translate
- CCarbon
- HHydrogen
- NNitrogen
- OOxygen
- SSulfur
Known Synonyms
Identifiers
Computed Properties
Melanotan II — Research Reference
A pan-melanocortin α-MSH analogue studied for potent melanogenesis (pigmentation) plus MC4R appetite and arousal effects.
What is Melanotan II?
Melanotan II (MT-II) is a synthetic cyclic heptapeptide analogue of α-melanocyte-stimulating hormone (α-MSH) and the most-published melanocortin agonist in research. Its signature documented effect is potent stimulation of melanin synthesis (skin pigmentation) via MC1R, and — because it activates all five melanocortin receptors — research also studies its MC4R-driven appetite-suppression and arousal effects. That broad receptor coverage makes it the benchmark probe across melanocortin-pathway research. Noxa Labs supplies MT-II as a third-party tested analytical reference material for in vitro research only. Note: this compound is supplied strictly as an analytical reference material for in vitro research by qualified professionals. It is not a pharmaceutical product, supplement, or substance for human or animal use.
Mechanism in research literature
MT-II is a pan-melanocortin agonist; its cyclic backbone enables high-affinity binding across MC1R (pigmentation), MC3R/MC4R (hypothalamic appetite and arousal circuits) and MC5R (peripheral). In melanocyte cultures it potently stimulates eumelanin synthesis through MC1R-coupled adenylyl-cyclase activation — the basis for its pigmentation effects — while in hypothalamic neuronal cultures it modulates POMC-pathway signalling tied to the appetite and arousal readouts. This breadth of engagement is what makes MT-II a versatile research probe and what distinguishes it from the more MC4R-selective PT-141.
Documented research applications
Documented research contexts include melanocyte cell-culture and melanogenesis-pathway assays, central melanocortin-signalling research (appetite, arousal), and comparative melanocortin pharmacology. Its pan-receptor profile makes it a benchmark in melanocortin structure-activity-relationship (SAR) research.
Reconstitution
Reconstitute lyophilised MT-II with bacteriostatic water. A common starting concentration is 10 mg/mL for a 10 mg vial in 1 mL BAC water. Swirl gently — do not shake — until fully dissolved.
Storage & stability
Store lyophilised MT-II at 2–8 °C. Reconstituted solution at 2–8 °C, used within 4 weeks.
Frequently asked questions
All Noxa Labs products are supplied strictly as analytical reference materials for qualified in vitro research. They are not pharmaceutical products, food supplements, or substances for human or animal consumption.
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