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Kisspeptin-10 — image 1
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4.9/5 from Philippine Researchers

Kisspeptin-10

₱2,829₱2,699

Kisspeptin-10 is studied for naturally stimulating sex hormones, libido, and fertility.

  • Stimulates natural sex hormones
  • Boosted libido & arousal
  • Supports fertility & reproductive health
  • Activates the LH/FSH hormone axis
  • Mood & wellbeing support
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Kisspeptin-10

PubChem CID: 25240297

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Kisspeptin-10

3D Structure

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  • CCarbon
  • HHydrogen
  • NNitrogen
  • OOxygen
  • SSulfur

Known Synonyms

Kisspeptin-10374675-21-5Kisspeptin-10 (human)FS1N52VS3SHuman metastin 45-54RefChem:1088060+ 4 more

Identifiers

Molecular Formula

C63H83N17O14

InChIKey

RITKWYDZSSQNJI-INXYWQKQSA-N

InChI

InChI=1S/C63H83N17O14/c1-34(2)24-45(...

Sequence

YNWNSFGLRF

Computed Properties

Molecular Weight1302.4
XLogP3-1.9
Hydrogen Bond Donor Count18
Hydrogen Bond Acceptor Count16
Rotatable Bond Count38
View all properties

Kisspeptin-10 — Research Reference

A decapeptide studied as the most potent natural trigger of GnRH and downstream LH/FSH release in reproductive research.

What is Kisspeptin-10?

Kisspeptin-10 (Kp-10) is the active C-terminal fragment of the KISS1 gene product and the most-used kisspeptin in reproductive-neuroendocrinology research. Studies document it as the most potent known stimulator of GnRH release — the upstream switch that drives the pituitary to secrete LH and FSH and, in turn, the gonadal hormone cascade — making it foundational to research on puberty timing and reproductive-cycle control. It is the shortest variant that retains full receptor activity at KISS1R. Noxa Labs supplies Kp-10 as a third-party tested analytical reference material for in vitro research only. Note: this compound is supplied strictly as an analytical reference material for in vitro research by qualified professionals. It is not a pharmaceutical product, supplement, or substance for human or animal use.

Mechanism in research literature

KISS1R is a Gq-coupled GPCR expressed densely on GnRH neurons. Kp-10 activation of these neurons triggers GnRH release, which drives anterior-pituitary LH and FSH secretion — the documented pathway behind its role as the proximal activator of the reproductive (HPG) axis. In cell-culture and rodent studies it is described as the most potent activator of the GnRH pulse generator. The short Kp-10 retains the C-terminal residues critical for receptor binding and is generally preferred to longer variants (Kp-54, -14, -13) for cost and synthesis efficiency.

Documented research applications

Documented research contexts include GnRH-pulse-generator electrophysiology, puberty-timing research in rodent models, reproductive-cycle and HPG-axis studies, hypothalamic neuropeptide co-localisation studies, and KISS1R signalling assays in cell-culture systems — with LH/FSH and GnRH output as recurring endpoints.

Reconstitution

Reconstitute lyophilised kisspeptin-10 with bacteriostatic water at a working concentration appropriate to your assay.

Storage & stability

Store lyophilised at 2–8 °C. Reconstituted solution at 2–8 °C, used within 3 weeks per typical batch stability windows.

Frequently asked questions

All Noxa Labs products are supplied strictly as analytical reference materials for qualified in vitro research. They are not pharmaceutical products, food supplements, or substances for human or animal consumption.

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Analytical-grade peptide reference materials for in vitro research. Third-party tested. COA-verified. PH delivery only.

Research Use Only

All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.

Noxa Labs Philippines is a research-chemical supplier operating under Republic Act 9711 (Food and Drug Administration Act of 2009). We do not manufacture, compound, dispense, or distribute pharmaceuticals, supplements, or health products subject to FDA Philippines registration. Products are supplied solely as analytical reference materials for in vitro research by qualified professionals.

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